Oral fosfomycin formulation for acute bacterial prostatitis; a new role for an old molecule: A case report and brief literature review

Acute and chronic bacterial prostatitis are considered infections which cumbersome to treat, due the limited available selection of effective antibiotics pharmacologically poor distribution in prostatic tissue. Furthermore, emergence novel antimicrobial resistance patterns, such as extended spectrum β‑lactamase (ESBL)‑producing Escherichia coli (E. coli) along with increasing fluoroquinolone poses major clinical concerns selecting appropriate therapy treat eradicate infection, particularly considering outpatient setting. The present study describes case a healthy male affected by first acute episode ESBL‑producing E. coli. patient was successfully treated oral fosfomycin‑trometamol administration, achieving success microbiological eradication. described study, literature review, encourage suggest use fosfomycin for treatment both prostatitis, outpatients those subjects who cannot be administered other antibiotics.